Pat Murphy may refer to:
Pat Murphy (writer) (born 1955), American science and science-fiction writer
Pat Murphy (baseball) (1857–1927), American baseball player
Pat Murphy (footballer, born 1906) (1906–1973), Australian rules footballer for Hawthorn, see List of Hawthorn Football Club players
Pat Murphy (footballer, born 1947), Australian rules footballer for St Kilda, see List of St Kilda Football Club players
Pat Murphy (baseball coach) (born 1958), American baseball coach
Pat Murphy (Iowa politician) (born 1959), American politician
Pat Murphy (Canadian politician) (elected 2007), member of the Legislative Assembly of Prince Edward Island
Pat Murphy (sports journalist), British sports writer and broadcaster
Pat Murphy (director) (born 1951), Irish film director
Pat Murphy (rugby union) (c. 1878 – c. 1945), Australian rugby union player