|Date of birth||Berlin, Germany|
|Date of death||Apr 21, 1892 Schwerin, Schwerin District, East Germany|
|Awards||Order of Louise|
Princess Alexandrine of Prussia (23 February 1803 – 21 April 1892) was Grand Duchess of Mecklenburg-Schwerin by marriage to Paul Frederick, Grand Duke of Mecklenburg-Schwerin. She was the daughter of Frederick William III of Prussia and Louise of Mecklenburg-Strelitz.
Alexandrine was the seventh child and fourth daughter of Frederick William III of Prussia and his wife Louise of Mecklenburg-Strelitz. She was a younger sister of Frederick William IV of Prussia, Wilhelm I of Prussia, and Charlotte, Empress of Russia.
On 25 May 1822, she married Paul Frederick of Mecklenburg-Schwerin. He succeeded his grandfather as Grand Duke of Mecklenburg-Schwerin in 1837.
Her marriage was generally considered unhappy; Paul Frederick was a military man who had little time for or interest in his wife and family. Alexandrine, by contrast, was a devoted mother who tenderly raised her children and actively cultivated their cultural pursuits. Alexandrine herself was very cultured but was also described as a stereotypically-remote German princess. She was not considered an intellectual but attended scholarly lectures and read many books.
At the time of her death, she was the last surviving grandchild of Frederick William II of Prussia. She saw several Prussian Kings in the length of her long life: they were Frederick William III (her father), Frederick William IV and Wilhelm I (brothers), Frederick III (nephew) and Wilhelm II (greatnephew). She also outlived her son and would die in the reign of her grandson Frederick Francis III.
Titles, styles, honours and arms
- Her Royal Highness Princess Alexandrine of Prussia (1803–1822)
- Her Royal Highness The Hereditary Grand Duchess of Mecklenburg-Schwerin (1822–1837)
- Her Royal Highness The Grand Duchess of Mecklenburg-Schwerin (1837–1842)
- Her Royal Highness The Dowager Grand Duchess of Mecklenburg-Schwerin (1842–1892)
- Dame of the Order of Louise