Thomas Wyndham may refer to:
Thomas Wyndham (of Felbrigg) (d. 1521), vice-admiral and councillor to Henry VIII
Thomas Wyndham (navigator) (d. 1554), navigator and son of Thomas Wyndham (of Felbrigg)
Thomas Wyndham (of Tale) (c.1628–1713), Member of Parliament for Minehead and Yarmouth (Isle of Wight)
Thomas Wyndham (of Witham Friary) (c. 1642–1689), Member of Parliament for Wells
Thomas Wyndham (lawyer) (1662–1698), Member of Parliament for Wilton
Thomas Wyndham, 1st Baron Wyndham (1681–1745), Lord Chancellor of Ireland
Thomas Wyndham (of Clearwell Park) (c.1686–1752), Member of Parliament for Dunwich and Truro
Thomas Wyndham (of Hammersmith) (c.1693–1777), Member of Parliament for Poole
Thomas Wyndham (of Dunraven Castle) (c.1768–1814), Member of Parliament for Glamorganshire