Sergio Zardini (November 22, 1931 – February 22, 1966) was an Italian bobsledder who competed from the late 1950s to the mid-1960s. He won the silver medal in the two-man event at the 1964 Winter Olympics in Innsbruck. He was born in Turin.
Zardini also won ten medals at the FIBT World Championships with one gold (Four-man: 1963), six silvers (Two-man: 1958, 1959, 1962, 1963; Four-man: 1959, 1962), and three bronzes (Two-man: 1960, 1961; Four-man: 1958).
Following the 1964 games, Zardini emigrated to Canada where he competed. He was killed during a competition two years later at the bobsleigh track in Lake Placid, New York when the Canadian four-man sled hit the superstructure of the track at Turns 13 and 14, known as the "Zig-Zag Curves", crushing his head against the structure.