James Strudwick Smith (October 15, 1790 – August 1859) was a Congressional Representative from North Carolina; born near Hillsboro, North Carolina, October 15, 1790; attended a private school near Hillsboro and Hillsboro Academy; was graduated from Jefferson Medical College, Philadelphia, Pennsylvania, in 1818, and practiced medicine near Hillsboro and later near Chapel Hill, North Carolina; elected as a Democratic-Republican to the Fifteenth and Sixteenth Congresses (March 4, 1817 – March 3, 1821); chairman, Committee on Accounts (Sixteenth Congress); unsuccessful candidate for renomination; resumed the practice of medicine; member of the State house of commons in 1821 and 1822; delegate to the State constitutional convention in 1835; died near Chapel Hill, N.C., in August 1859; interment in a private cemetery on his farm.